Dipeptidyl Peptidase

Peptidase

DPP

Dipeptidyl Peptidase

Dipeptidyl Peptidase Isoform Specific Products:

Dipeptidyl Peptidase Related Products (179)
Recombinant Proteins (8)
Antibodies (1)
Dipeptidyl Peptidase Isoform Comparison

By Effects:	Controls (7) Inhibitors (158) Substrates (3) Activator (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-A0299A

H-Gly-Pro-Hyp-OH acetate	Inhibitor
H-Gly-Pro-Hyp-OH acetate is a dipeptidyl peptidase 4 (DPP-4) inhibitor with an IC₅₀ value of 2.51 mM. H-Gly-Pro-Hyp-OH acetate is promising for research of diabetes.

HY-10284R

Linagliptin (Standard)	Inhibitor
Linagliptin (Standard) is the analytical standard of Linagliptin. This product is intended for research and analytical applications. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC₅₀ of 1 nM.

HY-10285S2

Saxagliptin-¹³C₂	Inhibitor
Saxagliptin-¹³C₂ (BMS-477118-¹³C₂) is ¹³C labeled Saxagliptin. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research.

HY-Z3637

(–)-Sitagliptin carbamoyl glucuronide	Control
(–)-Sitagliptin carbamoyl glucuronide is a minor metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor Sitagliptin (HY-13749).

HY-A0023AR

Alogliptin (Standard)	Inhibitor
Alogliptin (Standard) is the analytical standard of Alogliptin. This product is intended for research and analytical applications. Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with an IC₅₀ of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin can be used for the research of type 2 diabetes.

HY-P991050

Procizumab	Inhibitor
Procizumab (AK-1967) is a humanized IgG1 antibody that targets dipeptidyl peptidase 3 (DPP3). Procizumab has the potential for the study of sepsis. The isotype control for Procizumab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-N4069

Lupinalbin A	Inhibitor
Lupinalbin A (Boeravinone L) is a dipeptidyl peptidase 4 (DPP4) and α-glucosidase inhibitor with IC₅₀ values of 45.2 and 53.4 µM, respectively. Lupinalbin A exhibits antidiabetic activity.

HY-14291S

Vildagliptin-d₃	Inhibitor
Vildagliptin-d₃ is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1][2].

HY-135534

Lysine 4-nitroanilide
Lysine 4-nitroanilide is an amino acid derivative of 4-nitroanilide (component C1 substrate) used in enzymology research and as a substrate for arylamidase/DPP-3 activity assays.

HY-15981R

Omarigliptin (Standard)	Inhibitor
Omarigliptin (Standard) is the analytical standard of Omarigliptin. This product is intended for research and analytical applications. Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier dipeptidyl peptidase 4 (DPP-4) inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction.

HY-119266

HTS13517	Inhibitor
HTS13517 is a DPP4 inhibitor, with an IC₅₀ of 10.73 μM.

HY-13749BR

Sitagliptin (phosphate monohydrate) (Standard)	Inhibitor
Sitagliptin (phosphate monohydrate) (Standard) is the analytical standard of Sitagliptin (phosphate monohydrate). This product is intended for research and analytical applications. Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts.

HY-10285R

Saxagliptin (Standard)	Inhibitor
Saxagliptin (Standard) is the analytical standard of Saxagliptin. This product is intended for research and analytical applications. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research.

HY-109060

Garvagliptin	Inhibitor
Garvagliptin (ZYDPLA1) is an orally active, competitive and long acting DPP4 Inhibitor, with an IC₅₀ of 2.99 nM against human recombinant DPP IV. Garvagliptin (ZYDPLA1) exhibits antihyperglycemic effect.

HY-10284S4

Linagliptin-d₅	Inhibitor
Linagliptin-d₅ (BI 1356-d₅) is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC₅₀ of 1 nM.

HY-U00346A

TS-021	Inhibitor
TS-021 is a selective，orally active，reversible and long-acting DPP-IV inhibitor，and exhibits significant inhibition selectivity against DPP-8 (> 600 fold)，DPP-9 (> 1200 fold) and other peptidases (> 15,000 fold). TS-021 inhibits DPP-IV activity in human plasma with an IC₅₀ value of 5.34 nM. TS-021 has long-term persistent plasma drug concentration and potent antihyperglycemic activity，and increases in the active form of GLP-1.

HY-14291S5

Vildagliptin-d₆	Inhibitor
Vildagliptin-d₆ (LAF237-d₆ ) is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

HY-13749D

(Rac)-Sitagliptin	Inhibitor
(Rac)-Sitagliptin is an isoform of Sitagliptin (HY-13749), which is a potent and orally active inhibitor of DPP4 with an IC₅₀ of 19 nM in Caco-2 cell extracts.

HY-117985S

Evogliptin-d₉	Inhibitor
Evogliptin-d₉ (DA-1229-d₉) is deuterium labeled Evogliptin. Evogliptin (DA-1229) is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation.

Sitagliptin			DPP-4			99.75%
Talabostat mesylate			DPP-4			98.35%
Puromycin aminonucleoside		DPP-2				99.86%
Linagliptin			DPP-4			99.91%
Brensocatib	DPP-1					99.88%
Sitagliptin phosphate			DPP-4			99.79%
Diprotin A			DPP-4			99.58%
Vildagliptin			DPP-4			99.93%
1G244			DPP-4			98.50%
Omarigliptin			DPP-4			99.96%
Saxagliptin			DPP-4			99.96%
Teneligliptin			DPP-4			99.79%
Alogliptin Benzoate			DPP-4			99.99%
Sitagliptin phosphate monohydrate			DPP-4			99.49%
Alogliptin			DPP-4			99.85%
Nateglinide			DPP-4			99.51%
Trelagliptin			DPP-4			99.54%
Teneligliptin hydrobromide			DPP-4			99.99%
Anagliptin			DPP-4, IC₅₀: 3.8 nM	DPP-8, IC₅₀: 68 nM	DPP-9, IC₅₀: 60 nM	99.91%
Trelagliptin succinate			DPP-4			99.96%
γ-Glu-Tyr			DPP-4, IC₅₀: 6.77 mM			98.35%
K579			DPP-4			99.19%
Diprotin A TFA			DPP-4			99.62%
Evogliptin tartrate			DPP-4			99.71%
Saxagliptin hydrochloride			DPP-4			99.71%
Sitagliptin-d₄ phosphate			DPP-4			99.48%
Retagliptin phosphate			DPP-4			99.89%
TS-021 free base			DPP-4			99.29%
Gosogliptin			DPP-4			99.83%
Timosaponin A1			DPP-4, IC₅₀: 33.25 μM			99.70%
Sitagliptin fenilalanil			DPP-4			99.76%
Saxagliptin hydrate			DPP-4			≥99.0%
Cofrogliptin			DPP-4			99.07%
Azaleatin			DPP-4			98.80%
NZ-97			DPP-4, IC₅₀: 18 nM	DPP-8, IC₅₀: 1258 nM	DPP-9, IC₅₀: 561 nM	99.43%
Linagliptin-d₄			DPP-4			99.62%
Gemigliptin			DPP-4
Vildagliptin dihydrate			DPP-4
Talabostat			DPP-4
Fotagliptin benzoate			DPP-4, IC₅₀: 22.7 nM			99.19%
Alogliptin-d₃			DPP-4			99.61%
NDMC101			DPP-4			99.91%
HAEGT			DPP-4			98.86%
Alogliptin-¹³C,d₃			DPP-4
Teneligliptin-d₈			DPP-4
Nateglinide-d₅			DPP-4			≥98.0%
Prodipine hydrochloride			DPP-4			99.84%
Fotagliptin			DPP-4, IC₅₀: 2.27 nM			99.05%
Anagliptin hydrochloride			DPP-4, IC₅₀: 3.8 nM	DPP-8, IC₅₀: 68 nM	DPP-9, IC₅₀: 60 nM
(S)-Sitagliptin phosphate			DPP-4
PB01			DPP-4, IC₅₀: 15.66 nM
MPO-IN-6			DPP-4, IC₅₀: 31.02 μM
Vildagliptin-d₇			DPP-4
DPP-4/GPR119 modulator 1			DPP-4
Linagliptin-¹³C,d₃			DPP-4
DPP-4-IN-3			DPP-4
DPP-8/9 probe-1			DPP-4, IC₅₀: .44 μM ([1])	DPP-8, IC₅₀: 210 nM ([1])	DPP-9, IC₅₀: 15 nM ([1])
AMG-222			DPP-4
DPP-4-IN-1			DPP-4, IC₅₀: 49 nM
DPP8/9-IN-1				DPP-8, IC₅₀: 14 nM	DPP-9, IC₅₀: 298 nM
DPP-4-IN-10			DPP-4
DPP-4-IN-11			DPP-4, IC₅₀: 2.75 μM
DPP-4-IN-2			DPP-4, IC₅₀: 79 nM
Carmegliptin			DPP-4
DPP-4/GPR119 modulator 2			DPP-4
Propyl-GSK-2793660	DPP-1
Teneligliptin-d₄			DPP-4
P32/98 hemifumarate			DPP-4, Ki: 130 nM
Propyl-GSK-2793660 hydrochloride	DPP-1
SGP8			DPP-4
DPP-4-IN-12			DPP-4, IC₅₀: 2 nM
DPP-4-IN-8			DPP-4, Ki: 0.96 μM
VAMP			DPP-4, IC₅₀: 1 μM DPP-4, Kd: 6.89 μM
DPP-4-IN-15			DPP-4, IC₅₀: 8.24 μM
Epostatin		DPP-2
H-Gly-Pro-Hyp-OH acetate			DPP-4, IC₅₀: 2.51 mM
Lupinalbin A			DPP-4, IC₅₀: 45.2 μM
Vildagliptin-d₃			DPP-4
HTS13517			DPP-4, IC₅₀: 10.73 μM
TS-021			DPP-4

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Dipeptidyl Peptidase

Dipeptidyl Peptidase

Dipeptidyl Peptidase Isoform Specific Products:

Dipeptidyl Peptidase Isoform Specific Products:

Dipeptidyl Peptidase Related Products (179)

Recombinant Proteins (8)

Antibodies (1)

Dipeptidyl Peptidase Isoform Comparison

Dipeptidyl Peptidase Related Products (179):